Services Overview

CGH Services
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HerScan™ for Breast Cancer

Chronic lymphocytic leukemia (CLL)

ATScan™ for Autism

Array comparative genomic hybridization (aCGH) is a sophisticated form of genetic testing that compares a patient sample to a normal reference sample to identify any genomic copy number changes. Genomic copy number changes, both increases and decreases in genetic content, are characteristic of almost all chromosomal abnormalities. Chromosome rearrangements such as whole chromosome aneuploidy, deletions and duplications are readily identified by aCGH. In addition, aCGH will identify many submicroscopic rearrangements that are undetectable using routine karyotype analysis, including those that occur at the subtelomeres. The advantage of aCGH over conventional genetic analyses is the large number of genetic loci that can be simultaneously evaluated, and the ability to identify abnormalities at a higher resolution.

CMDX’s Constitutional Genetic Array Test (CGAT) utilizes the aCGH technology to identify global chromosomal features and structural abnormalities associated with 61 specific congenital syndromes.